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Clinical and Radiological Discrimination of Solitary Pulmonary Lesions in Colorectal Cancer Patients.
- Source :
-
World journal of surgery [World J Surg] 2018 Apr; Vol. 42 (4), pp. 1161-1170. - Publication Year :
- 2018
-
Abstract
- Objectives: The lung is one of the most common organs of metastasis from colorectal cancer (CRC), and we have encountered lung cancer patients with a history of CRC. There have been few studies regarding methods used to discriminate between primary lung cancer (PLC) and pulmonary metastasis from CRC (PM-CRC) based only on preoperative findings. We retrospectively investigated predictive factors discriminating between these lesions in patients with a history of CRC.<br />Methods: Between 2006 and 2015, 117 patients with a history of CRC (44 patients with 47 PLC and 73 patients with 102 PM-CRC) underwent subsequent or concurrent resection of pulmonary lesions. We compared the clinical and radiological characteristics of 100 patients with solitary lesions (43 PLC and 57 PM-CRC). Using univariate and multivariate analyses, we examined predictive factors for discrimination of these two lesions.<br />Results: All tumors with findings of ground-glass opacity (GGO) were PLC (n = 19). In a multivariate analysis of 81 radiologically solid tumors, two factors were found to be significant independent predictors of PLC: a history of stage I CRC and presence of pleural indentation. All tumors in 26 patients with either GGO or both a stage I CRC history and pleural indentation were PLC, while most tumors in patients without all three factors were PM-CRC (43/44; 97.7%).<br />Conclusions: The presence or absence of GGO, pathological CRC stage, and pleural indentation could be useful factors to distinguish between PLC and PM-CRC.
- Subjects :
- Adult
Aged
Aged, 80 and over
Female
Humans
Lung
Male
Middle Aged
Multivariate Analysis
Neoplasm Metastasis
Neoplasm Staging
Pleura pathology
Prognosis
Radiography
Retrospective Studies
Tomography, X-Ray Computed
Treatment Outcome
Colorectal Neoplasms diagnostic imaging
Colorectal Neoplasms pathology
Lung Neoplasms diagnostic imaging
Lung Neoplasms pathology
Solitary Pulmonary Nodule diagnostic imaging
Solitary Pulmonary Nodule secondary
Subjects
Details
- Language :
- English
- ISSN :
- 1432-2323
- Volume :
- 42
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- World journal of surgery
- Publication Type :
- Academic Journal
- Accession number :
- 28983707
- Full Text :
- https://doi.org/10.1007/s00268-017-4243-9