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Phosphinoyl Radical Initiated Vicinal Cyanophosphinoylation of Alkenes.

Authors :
Zhang PZ
Zhang L
Li JA
Shoberu A
Zou JP
Zhang W
Source :
Organic letters [Org Lett] 2017 Oct 20; Vol. 19 (20), pp. 5537-5540. Date of Electronic Publication: 2017 Oct 02.
Publication Year :
2017

Abstract

A double-functionalization reaction of alkenes through Mn(OAc) <subscript>3</subscript> -mediated phosphinoyl radical addition followed by CuCN-catalyzed cyanation is introduced. This one-pot reaction is performed under mild conditions to afford vicinal cyanophosphinoylation products.

Details

Language :
English
ISSN :
1523-7052
Volume :
19
Issue :
20
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
28968118
Full Text :
https://doi.org/10.1021/acs.orglett.7b02621