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Direct Synthesis of Amides by Dehydrogenative Coupling of Amines with either Alcohols or Esters: Manganese Pincer Complex as Catalyst.

Authors :
Kumar A
Espinosa-Jalapa NA
Leitus G
Diskin-Posner Y
Avram L
Milstein D
Source :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Nov 20; Vol. 56 (47), pp. 14992-14996. Date of Electronic Publication: 2017 Oct 20.
Publication Year :
2017

Abstract

The first example of base-metal-catalysed synthesis of amides from the coupling of primary amines with either alcohols or esters is reported. The reactions are catalysed by a new manganese pincer complex and generate hydrogen gas as the sole byproduct, thus making the overall process atom-economical and sustainable.<br /> (© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)

Details

Language :
English
ISSN :
1521-3773
Volume :
56
Issue :
47
Database :
MEDLINE
Journal :
Angewandte Chemie (International ed. in English)
Publication Type :
Academic Journal
Accession number :
28967992
Full Text :
https://doi.org/10.1002/anie.201709180