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Antiaflatoxigenic and Antimicrobial Activities of Schiff Bases of 2-Hydroxy-4-methoxybenzaldehyde, Cinnamaldehyde, and Similar Aldehydes.
- Source :
-
Journal of agricultural and food chemistry [J Agric Food Chem] 2017 Oct 11; Vol. 65 (40), pp. 8773-8778. Date of Electronic Publication: 2017 Oct 03. - Publication Year :
- 2017
-
Abstract
- 2-Hydroxy-4-methoxybenzaldehyde (HMBA) is a nontoxic phenolic flavor from dietary source Decalipus hamiltonii and Hemidesmus indicus. HMBA is an excellent antimicrobial agent with additional antiaflatoxigenic potency. On the other hand, cinnamaldehyde from cinnamon is a widely employed flavor with significant antiaflatoxigenic activity. We have attempted the enhancement of antiaflatoxigenic and antimicrobial properties of HMBA, cinnamaldehyde, and similar molecules via Schiff base formation accomplished from condensation reaction with amino sugar (d-glucamine). HMBA derived Schiff bases exhibited commendable antiaflatoxigenic activity at the concentration 0.1 mg/mL resulting in 9.6 ± 1.9% growth of Aspergillus flavus and subsequent 91.4 ± 3.9% reduction of aflatoxin B <subscript>1</subscript> with respect to control.
- Subjects :
- Acrolein chemistry
Acrolein pharmacology
Aflatoxin B1 metabolism
Aldehydes chemistry
Aldehydes pharmacology
Antifungal Agents chemistry
Aspergillus flavus growth & development
Aspergillus flavus metabolism
Benzaldehydes chemistry
Molecular Structure
Plant Extracts chemistry
Schiff Bases chemistry
Schiff Bases pharmacology
Acrolein analogs & derivatives
Antifungal Agents pharmacology
Apocynaceae chemistry
Aspergillus flavus drug effects
Benzaldehydes pharmacology
Cinnamomum zeylanicum chemistry
Hemidesmus chemistry
Plant Extracts pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1520-5118
- Volume :
- 65
- Issue :
- 40
- Database :
- MEDLINE
- Journal :
- Journal of agricultural and food chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 28942637
- Full Text :
- https://doi.org/10.1021/acs.jafc.7b02576