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Peripapillary Choroidal Thickness Analysis Using Swept-Source Optical Coherence Tomography in Glaucoma Patients: A Broader Approach.
- Source :
-
Ophthalmic research [Ophthalmic Res] 2018; Vol. 59 (1), pp. 7-13. Date of Electronic Publication: 2017 Sep 23. - Publication Year :
- 2018
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Abstract
- Aims: To evaluate and compare peripapillary choroidal thickness (PPCT) in a wide area around the optic disk and various choroidal established zones in healthy controls and primary open-angle glaucoma (POAG) patients using a new swept-source (SS) optical coherence tomography (OCT) device.<br />Methods: A total of 246 eyes were finally included in this observational, prospective, cross-sectional study: 111 healthy controls and 135 POAG patients. The healthy subjects were divided into 2 populations: the teaching population (25 used to establish choroidal zones) and the validating population (86 used for comparing choroidal thickness with POAG patients). A 26 × 26 cube grid centered on the optic disk was generated using an SS-OCT to automatically measure choroidal thickness. Four choroidal zones were established and used to compare PPCT between healthy controls and POAG patients.<br />Results: PPCT was significantly thinner in zones 3 and 4 of the POAG group. The choroid exhibited a similar pattern in controls and patients with POAG; it was thickest in the superior region, followed in order by the temporal, nasal, and inferior regions.<br />Conclusions: Peripapillary choroidal tissue shows a concentric pattern in both groups, and glaucoma patients present with peripapillary choroidal thinning compared with healthy subjects, especially in areas further away from the optic disk.<br /> (© 2017 S. Karger AG, Basel.)
Details
- Language :
- English
- ISSN :
- 1423-0259
- Volume :
- 59
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Ophthalmic research
- Publication Type :
- Academic Journal
- Accession number :
- 28942454
- Full Text :
- https://doi.org/10.1159/000479877