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A novel guidewire-integrated embolic protection filter device with a handy-folding system: In vitro and in vivo performance assessment.
- Source :
-
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions [Catheter Cardiovasc Interv] 2018 Jul; Vol. 92 (1), pp. E9-E14. Date of Electronic Publication: 2017 Sep 20. - Publication Year :
- 2018
-
Abstract
- Objectives: We developed a novel guidewire-integrated filter device with a handy-folding system (IFD: Inoue filter device). In vitro and in vivo studies were conducted to evaluate the feasibilityof the IFD.<br />Background: Although distal atheromatous and thrombotic embolizations remain unresolved critical issues during catheter interventions, distal protection devices are infrequently used partly because of reduced lower maneuverability.<br />Methods: In the in vitro experiment, we created an experimental circulation model composed of silicone latex tubes, a reservoir, and a roller pump. After the filter device was deployed in the tube, polystyrene fluorescent microspheres were injected and the capture rate was calculated. Ten trials were performed using the IFD and Spider FX. In the in vivo study, five independent operators deployed, and they retrieved the IFD in swine common iliac and internal carotid arteries. The procedural success rate as well as the delivery and retrieval time was evaluated.<br />Results: In the in vitro study, the mean capture rate was 94% and 35% in the IFD and Spider groups, respectively. In the in vivo study, all procedures were successful, with no complications. The mean delivery time was 281 ± 87 s and 194 ± 67 s and the mean retrieval time was 24 ± 9 and 13 ±1 s in the left internal carotid and the left common iliac arteries, respectively.<br />Conclusion: Although further studies and improvements are required, the study results indicate that the IFD is feasible.<br /> (© 2017 Wiley Periodicals, Inc.)
- Subjects :
- Angiography
Animals
Cardiac Catheterization adverse effects
Catheterization, Peripheral adverse effects
Device Removal
Materials Testing
Models, Anatomic
Models, Animal
Models, Cardiovascular
Prosthesis Design
Sus scrofa
Time Factors
Cardiac Catheterization instrumentation
Carotid Artery, Internal diagnostic imaging
Catheterization, Peripheral instrumentation
Embolic Protection Devices
Iliac Artery diagnostic imaging
Vascular Access Devices
Subjects
Details
- Language :
- English
- ISSN :
- 1522-726X
- Volume :
- 92
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
- Publication Type :
- Academic Journal
- Accession number :
- 28940984
- Full Text :
- https://doi.org/10.1002/ccd.27315