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Outcomes of Therapy for Vulvar Manifestation of Inflammatory Bowel Disease in Adolescents.
- Source :
-
Journal of pediatric and adolescent gynecology [J Pediatr Adolesc Gynecol] 2018 Apr; Vol. 31 (2), pp. 149-152. Date of Electronic Publication: 2017 Sep 15. - Publication Year :
- 2018
-
Abstract
- Background: Vulvar manifestations of inflammatory bowel disease (IBD) are variable in presentation and challenging to treat. We describe vulvar manifestations and treatment response in female adolescents with IBD.<br />Cases: We identified 6 patients with vulvar manifestations of IBD and documented treatments using retrospective chart review. Vulvar symptoms occurred without gastrointestinal (GI) symptoms in 1 patient. For the remaining 5 patients, 2 had GI symptoms before the onset of vulvar symptoms (mean time difference, 4.5 years); 3 patients had vulvar symptoms precede the onset of GI symptoms (mean time difference, 3.3 years). Vulvar IBD manifestations included pain, 100% (n = 6); enlargement, "fullness" or "edema" of the labia minora or majora, 66% (n = 4); ulcers, 50% (n = 3); and abscess, 50% (n = 3). Gynecologic procedures included biopsies, incision and drainages, and partial vulvectomies. All patients were treated with multiple systemic therapies. None of the patients responded to surgical or medical treatment alone; all had recalcitrant vulvar symptoms.<br />Summary and Conclusion: Vulvar manifestations of IBD might precede GI symptoms in adolescents with IBD. Treatment is challenging and in this series, systemic therapies were the most successful in achieving symptomatic improvement.<br /> (Copyright © 2017 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1873-4332
- Volume :
- 31
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of pediatric and adolescent gynecology
- Publication Type :
- Academic Journal
- Accession number :
- 28919145
- Full Text :
- https://doi.org/10.1016/j.jpag.2017.08.008