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Helicases as transcription termination factors: Different solutions for a common problem.

Authors :
Han Z
Porrua O
Source :
Transcription [Transcription] 2018; Vol. 9 (3), pp. 152-158. Date of Electronic Publication: 2017 Oct 04.
Publication Year :
2018

Abstract

Helicases are enzymes that remodel nucleic acids or protein-nucleic acid complexes in an ATP-dependent manner. They are ubiquitous and can play many diverse functions related to the metabolism of nucleic acids. A few helicases from both the prokaryotic and the eukaryotic worlds have the ability to induce transcription termination. Here we discuss how the same biological function is achieved by different helicases with quite divergent structures and mechanisms of action.

Details

Language :
English
ISSN :
2154-1272
Volume :
9
Issue :
3
Database :
MEDLINE
Journal :
Transcription
Publication Type :
Academic Journal
Accession number :
28886303
Full Text :
https://doi.org/10.1080/21541264.2017.1361503