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Livedoid eruption in a patient affected by T-γδ large granular lymphocyte leukaemia.
- Source :
-
BMJ case reports [BMJ Case Rep] 2017 Sep 07; Vol. 2017. Date of Electronic Publication: 2017 Sep 07. - Publication Year :
- 2017
-
Abstract
- Livedo is an ischaemic dermopathy characterised by a reddish-blue to violaceous mottling of the skin with a net-like reticular appearance. Livedo has been described in association with several medical conditions including lymphoproliferative disorders. Here, we describe the case of a 60-year-old woman who was presented with asymptomatic and persistent livedoid eruption on her trunk, lower and upper extremities as manifestation of an indolent form of T-γδ large granular lymphocyte leukaemia. To the best of our knowledge, this is the first report describing the association between livedo reticularis and T-γδ large granular lymphocyte leukaemia. It is plausible that a pathogenetic role of the neoplastic process is based on a cytotoxic antiendothelial activity.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)
- Subjects :
- Diagnosis, Differential
Female
Humans
Leukemia, Large Granular Lymphocytic complications
Leukemia, Large Granular Lymphocytic therapy
Livedo Reticularis drug therapy
Lymphoproliferative Disorders complications
Lymphoproliferative Disorders pathology
Middle Aged
Treatment Outcome
Leukemia, Large Granular Lymphocytic pathology
Livedo Reticularis etiology
Livedo Reticularis pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1757-790X
- Volume :
- 2017
- Database :
- MEDLINE
- Journal :
- BMJ case reports
- Publication Type :
- Academic Journal
- Accession number :
- 28882931
- Full Text :
- https://doi.org/10.1136/bcr-2017-220051