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Livedoid eruption in a patient affected by T-γδ large granular lymphocyte leukaemia.

Authors :
Biolo G
Sacco G
Russo I
Alaibac M
Source :
BMJ case reports [BMJ Case Rep] 2017 Sep 07; Vol. 2017. Date of Electronic Publication: 2017 Sep 07.
Publication Year :
2017

Abstract

Livedo is an ischaemic dermopathy characterised by a reddish-blue to violaceous mottling of the skin with a net-like reticular appearance. Livedo has been described in association with several medical conditions including lymphoproliferative disorders. Here, we describe the case of a 60-year-old woman who was presented with asymptomatic and persistent livedoid eruption on her trunk, lower and upper extremities as manifestation of an indolent form of T-γδ large granular lymphocyte leukaemia. To the best of our knowledge, this is the first report describing the association between livedo reticularis and T-γδ large granular lymphocyte leukaemia. It is plausible that a pathogenetic role of the neoplastic process is based on a cytotoxic antiendothelial activity.<br />Competing Interests: Competing interests: None declared.<br /> (© BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)

Details

Language :
English
ISSN :
1757-790X
Volume :
2017
Database :
MEDLINE
Journal :
BMJ case reports
Publication Type :
Academic Journal
Accession number :
28882931
Full Text :
https://doi.org/10.1136/bcr-2017-220051