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[Analysis of clinical use of post-marketing hospital centralized monitoring of Xiyanping injection].

Authors :
Zhao Y
Shi C
Huang P
Source :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica [Zhongguo Zhong Yao Za Zhi] 2016 Feb; Vol. 41 (4), pp. 743-747.
Publication Year :
2016

Abstract

To assess the clinical use and occurrence of adverse reactions of Xiyanping injection, and to provide reference for rational drug use in the clinic. Based on hospital central monitoring method, the clinical data of Xiyanping injection in our hospital in 2014 was tracked and analyzed. A total of 848 inpatients were enrolled in this study. Among them, 39.9% were not in accordance with the medication purpose. In practice, the dose more than the limits prescribed by the instructions of child and adult were accounted for 1.72% and 6.62%, respectively; improper choice of solvent, accounting for 3.18%; both the choice of versus intravenous drip and aerosol inhalati administration route were reasonable; mixed with other drug, accounting for 2.24%. The incidence of ADR of Xiyanping injection was 0.12%, which showed good safety. Irrational use of Xiyanping injection existed in clinics, and the use should be strengthened and regulated. The manufacturer should improve the drug instruction of usage and dosage.<br />Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.<br /> (Copyright© by the Chinese Pharmaceutical Association.)

Details

Language :
Chinese
ISSN :
1001-5302
Volume :
41
Issue :
4
Database :
MEDLINE
Journal :
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
Publication Type :
Academic Journal
Accession number :
28871704
Full Text :
https://doi.org/10.4268/cjcmm20160434