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Moderate, but not vigorous, intensity exercise training reduces C-reactive protein.

Authors :
Fedewa MV
Hathaway ED
Higgins S
Forehand RL
Schmidt MD
Evans EM
Source :
Acta cardiologica [Acta Cardiol] 2018 Jun; Vol. 73 (3), pp. 283-290. Date of Electronic Publication: 2017 Aug 28.
Publication Year :
2018

Abstract

Background: Sprint interval cycle training is a contemporary popular mode of training but its relative efficacy, under conditions of matched energy expenditure, to reduce risk factors for cardiometabolic disease is incompletely characterised, especially in young women. The purpose of this investigation was to determine the relative efficacy of six weeks of moderate-intensity cycling (MOD-C) and vigorous sprint-interval cycling (VIG-SIC) on lipid profile, insulin (INS) and insulin resistance using the homeostatic model assessment (HOMA-IR) and C-reactive protein (CRP) in inactive, overweight/obese (OW/OB) young women.<br />Methods: Participants (BMI ≥25 kg/m <superscript>2</superscript> , waist circumference ≥88 cm) were randomly assigned to MOD-C (20-30 min at 60-70% of heart rate reserve(HRR)) or VIG-SIC (5-7 repeated bouts 30-second maximal effort sprints, followed by four minutes of active recovery) supervised training three days/week for six weeks, with each group matched on energy expenditure. Adiposity (%Fat) was measured using dual x-ray absorptiometry.<br />Results: Forty-four participants (20.4 ± 1.6 years, 65.9% Caucasian, 29.8 ± 4.1 kg/m <superscript>2</superscript> ) were included in the analysis. The improvement in CRP observed in the MOD-C group was larger than the VIG-C group (p = .034). Overall, high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) levels improved following training (p < .05); however, total cholesterol, triglyceride, INS and HOMA-IR did not improve (p > .05).<br />Conclusion: These results indicate MOD-C training may be more effective in reducing CRP than VIG-SIC.

Details

Language :
English
ISSN :
0001-5385
Volume :
73
Issue :
3
Database :
MEDLINE
Journal :
Acta cardiologica
Publication Type :
Academic Journal
Accession number :
28847205
Full Text :
https://doi.org/10.1080/00015385.2017.1364832