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An Unprecedented Blue Chromophore Found in Nature using a "Chemistry First" and Molecular Networking Approach: Discovery of Dactylocyanines A-H.
- Source :
-
Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2017 Oct 17; Vol. 23 (58), pp. 14454-14461. Date of Electronic Publication: 2017 Sep 19. - Publication Year :
- 2017
-
Abstract
- Guided by a "chemistry first" approach using molecular networking, eight new bright-blue colored natural compounds, namely dactylocyanines A-H (3-10), were isolated from the Polynesian marine sponge Dactylospongia metachromia. Starting from ilimaquinone (1), an hemisynthetic phishing probe (2) was prepared for annotating and matching structurally related natural substances in D. metachromia crude extract network. This strategy allowed characterizing for the first time in Nature the blue zwitterionic quinonoid chromophore. The solvatochromic properties of the latter are reported.<br /> (© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.)
- Subjects :
- Animals
Biological Products chemical synthesis
Biological Products chemistry
Biological Products isolation & purification
Chlortetracycline chemical synthesis
Chlortetracycline isolation & purification
Chromatography, High Pressure Liquid
Crystallography, X-Ray
Magnetic Resonance Spectroscopy
Molecular Conformation
Porifera metabolism
Quinones chemistry
Sesquiterpenes chemistry
Tandem Mass Spectrometry
Chlortetracycline analogs & derivatives
Porifera chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1521-3765
- Volume :
- 23
- Issue :
- 58
- Database :
- MEDLINE
- Journal :
- Chemistry (Weinheim an der Bergstrasse, Germany)
- Publication Type :
- Academic Journal
- Accession number :
- 28815818
- Full Text :
- https://doi.org/10.1002/chem.201702336