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Evaluation of hyoscine N-butyl bromide efficacy on the prevention of catheter-related bladder discomfort after transurethral resection of prostate: a randomized, double-blind control trial.
- Source :
-
International urology and nephrology [Int Urol Nephrol] 2017 Nov; Vol. 49 (11), pp. 1907-1913. Date of Electronic Publication: 2017 Aug 14. - Publication Year :
- 2017
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Abstract
- Background: Transurethral resection of prostate (TURP) is the most common treatment for benign prostatic hyperplasia (BPH). Urinary tract catheter is inserted post-operatively which results in catheter-related bladder discomfort (CRBD) in many patients. The purpose of this study was to assess the preventive effect of hyoscine N-butyl bromide on CRBD caused by a urinary tract catheter after TURP surgery in patients with BPH.<br />Methods: Twenty-four and twenty-six patients in the treatment and control groups were enrolled, respectively. At the end of the surgery, slow intravenous injection of 20 mg hyoscine N-butyl bromide was administered to the patients of treatment group. The severity of CRBD was followed up at five different time periods and up to 2 h after surgery.<br />Results: On arrival to PACU and after 30 min of injection, statistically significant less CRBD was seen in the treatment group comparing to the control group (P ≤ 0.05 and P ≤ 0.007). The total utilized meperidine dose during PACU stay and the time to discharge for the intervention group were significantly lower than those for the control group (P ≤ 0.0001) with no significant difference in adverse effects (P > 0.05).<br />Conclusions: Hyoscine N-butyl bromide could reduce the severity of CRBD related to TURP in patients with BPH and their need for analgesic consumption either. It shortened the length of stay in the recovery room. Regarding its availability and low cost, it can be an effective pain relief drug for CRBD discomfort related to TURP in BPH patients.
- Subjects :
- Aged
Analgesics, Opioid administration & dosage
Double-Blind Method
Humans
Male
Meperidine administration & dosage
Middle Aged
Pain Measurement
Pain, Postoperative etiology
Transurethral Resection of Prostate
Butylscopolammonium Bromide therapeutic use
Catheters, Indwelling adverse effects
Pain, Postoperative prevention & control
Parasympatholytics therapeutic use
Prostatic Hyperplasia surgery
Urinary Catheters adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1573-2584
- Volume :
- 49
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- International urology and nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 28808847
- Full Text :
- https://doi.org/10.1007/s11255-017-1663-2