Back to Search
Start Over
2015/16 seasonal vaccine effectiveness against hospitalisation with influenza A(H1N1)pdm09 and B among elderly people in Europe: results from the I-MOVE+ project.
- Source :
-
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2017 Jul 27; Vol. 22 (30). - Publication Year :
- 2017
-
Abstract
- We conducted a multicentre test-negative case-control study in 27 hospitals of 11 European countries to measure 2015/16 influenza vaccine effectiveness (IVE) against hospitalised influenza A(H1N1)pdm09 and B among people aged ≥ 65 years. Patients swabbed within 7 days after onset of symptoms compatible with severe acute respiratory infection were included. Information on demographics, vaccination and underlying conditions was collected. Using logistic regression, we measured IVE adjusted for potential confounders. We included 355 influenza A(H1N1)pdm09 cases, 110 influenza B cases, and 1,274 controls. Adjusted IVE against influenza A(H1N1)pdm09 was 42% (95% confidence interval (CI): 22 to 57). It was 59% (95% CI: 23 to 78), 48% (95% CI: 5 to 71), 43% (95% CI: 8 to 65) and 39% (95% CI: 7 to 60) in patients with diabetes mellitus, cancer, lung and heart disease, respectively. Adjusted IVE against influenza B was 52% (95% CI: 24 to 70). It was 62% (95% CI: 5 to 85), 60% (95% CI: 18 to 80) and 36% (95% CI: -23 to 67) in patients with diabetes mellitus, lung and heart disease, respectively. 2015/16 IVE estimates against hospitalised influenza in elderly people was moderate against influenza A(H1N1)pdm09 and B, including among those with diabetes mellitus, cancer, lung or heart diseases.<br /> (This article is copyright of The Authors, 2017.)
- Subjects :
- Aged
Aged, 80 and over
Europe epidemiology
Female
Humans
Influenza A Virus, H1N1 Subtype isolation & purification
Influenza B virus isolation & purification
Influenza Vaccines immunology
Influenza, Human epidemiology
Influenza, Human virology
Logistic Models
Male
Outcome Assessment, Health Care
Seasons
Sentinel Surveillance
Vaccination statistics & numerical data
Hospitalization statistics & numerical data
Influenza A Virus, H1N1 Subtype immunology
Influenza B virus immunology
Influenza Vaccines administration & dosage
Influenza, Human prevention & control
Vaccine Potency
Subjects
Details
- Language :
- English
- ISSN :
- 1560-7917
- Volume :
- 22
- Issue :
- 30
- Database :
- MEDLINE
- Journal :
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
- Publication Type :
- Academic Journal
- Accession number :
- 28797322
- Full Text :
- https://doi.org/10.2807/1560-7917.ES.2017.22.30.30580