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Successful salvage chemotherapy and allogeneic transplantation of an acute myeloid leukemia patient with disseminated Fusarium solani infection.

Authors :
Sheela S
Ito S
Strich JR
Manion M
Montemayor-Garcia C
Wang HW
Oetjen KA
West KA
Barrett AJ
Parta M
Gea-Banacloche J
Holland SM
Hourigan CS
Lai C
Source :
Leukemia research reports [Leuk Res Rep] 2017 Jul 18; Vol. 8, pp. 4-6. Date of Electronic Publication: 2017 Jul 18 (Print Publication: 2017).
Publication Year :
2017

Abstract

Disseminated Fusarium infection is associated with high mortality in immunocompromised patients. Patients with acute myeloid leukemia (AML) often have an extended duration of neutropenia during intensive induction chemotherapy, consolidation chemotherapy, and hematopoietic stem cell transplantation (SCT). There is no consensus regarding management of invasive disseminated Fusarium infections in the setting of prolonged neutropenia (Tortorano et al., 2014) [1]. We report a case of disseminated Fusarium in a patient with relapsed AML who underwent successful chemotherapy and haplo-identical allogeneic SCT with administration of granulocyte colony stimulating factor (G-CSF) and granulocyte infusions.

Details

Language :
English
ISSN :
2213-0489
Volume :
8
Database :
MEDLINE
Journal :
Leukemia research reports
Publication Type :
Report
Accession number :
28794968
Full Text :
https://doi.org/10.1016/j.lrr.2017.07.001