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Intravascular lymphoma with a gastric submucosal tumor.
- Source :
-
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology [Nihon Shokakibyo Gakkai Zasshi] 2017; Vol. 114 (8), pp. 1446-1453. - Publication Year :
- 2017
-
Abstract
- A 75-year-old man was admitted to our hospital for further examination of swollen lymph nodes and a possible gastric submucosal tumor. He had persistent fever and anorexia. Blood examination showed anemia, thrombocytopenia, and elevated lactate dehydrogenase and soluble interleukin 2 receptor levels. Swollen lymph nodes and splenomegaly were evident on computed tomography, and the submucosal tumor was revealed by esophagogastric endoscopy. Cervical lymph node biopsy and endoscopic biopsy were performed, which revealed a diagnosis of intravascular lymphoma. In Asian countries, patients with intravascular lymphoma often have hemophagocytic syndrome without lesions of the central nervous system or skin, which is called the Asian variant of intravascular lymphoma. In this case, the patient had no indicative lesions and had no evidence of the hemophagocytic syndrome. He also had lymph node swelling and a gastric submucosal tumor, which are rare in intravascular lymphoma. The patient was treated with chemotherapy (R-CHOP;rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisolone), and complete response was demonstrated (based on the Response Evaluation Criteria for Solid Tumours [RECIST] guideline). In cases of possible intravascular lymphoma, gastrointestinal endoscopy and biopsy should be considered because they are a useful diagnostic strategy.
- Subjects :
- Aged
Biopsy
Gastric Mucosa blood supply
Gastric Mucosa diagnostic imaging
Humans
Lymphoma diagnostic imaging
Male
Positron-Emission Tomography
Stomach Neoplasms blood supply
Stomach Neoplasms diagnostic imaging
Stomach Neoplasms pathology
Tomography, X-Ray Computed
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Gastric Mucosa pathology
Lymphoma drug therapy
Stomach Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0446-6586
- Volume :
- 114
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
- Publication Type :
- Academic Journal
- Accession number :
- 28781355
- Full Text :
- https://doi.org/10.11405/nisshoshi.114.1446