Sex differences in age-related changes in the sleep-wake cycle.

Authors :: Carrier J
Semba K
Deurveilher S
Drogos L
Cyr-Cronier J
Lord C
Sekerovick Z
Source :: Frontiers in neuroendocrinology [Front Neuroendocrinol] 2017 Oct; Vol. 47, pp. 66-85. Date of Electronic Publication: 2017 Jul 27.
Publication Year :: 2017
Abstract: Age-related changes in sleep and circadian regulation occur as early as the middle years of life. Research also suggests that sleep and circadian rhythms are regulated differently between women and men. However, does sleep and circadian rhythms regulation age similarly in men and women? In this review, we present the mechanisms underlying age-related differences in sleep and the current state of knowledge on how they interact with sex. We also address how testosterone, estrogens, and progesterone fluctuations across adulthood interact with sleep and circadian regulation. Finally, we will propose research avenues to unravel the mechanisms underlying sex differences in age-related effects on sleep.<br /> (Copyright © 2017 Elsevier Inc. All rights reserved.)