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Histology-Based Assessment of Sonazoid-Enhanced Ultrasonography for the Diagnosis of Liver Metastasis.
- Source :
-
Ultrasound in medicine & biology [Ultrasound Med Biol] 2017 Oct; Vol. 43 (10), pp. 2151-2158. Date of Electronic Publication: 2017 Jul 26. - Publication Year :
- 2017
-
Abstract
- This retrospective study aimed to assess the diagnostic performance of contrast-enhanced ultrasound with Sonazoid (S-CEUS) for liver metastasis. We enrolled in this study 98 patients with 148 histologically proven liver lesions, with 121 metastases and 27 non-metastases. The S-CEUS technique showed sensitivity in 95.0% (115 of 121), specificity in 44.4% (12 of 27) and accuracy in 85.8% (127 of 148) for the diagnosis of metastasis. Higher body mass index had a negative influence on the positive predictive value and accuracy, and a greater depth of the lesion had a negative influence on the accuracy. The management was changed in 8 patients (8.2%) because of S-CEUS findings. In conclusion, the addition of S-CEUS may offer a great benefit by improvement of the quality of diagnosis and management for patients with cancer who have a tentative diagnosis of liver metastasis by contrast-enhanced computed tomography.<br /> (Copyright © 2017 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Adult
Aged
Aged, 80 and over
Female
Humans
Liver diagnostic imaging
Male
Middle Aged
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity
Young Adult
Contrast Media
Ferric Compounds
Image Enhancement methods
Iron
Liver Neoplasms diagnostic imaging
Liver Neoplasms secondary
Oxides
Ultrasonography methods
Subjects
Details
- Language :
- English
- ISSN :
- 1879-291X
- Volume :
- 43
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Ultrasound in medicine & biology
- Publication Type :
- Academic Journal
- Accession number :
- 28755791
- Full Text :
- https://doi.org/10.1016/j.ultrasmedbio.2017.06.014