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Gastric mucus glycoprotein in different rat strains.
- Source :
-
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology [Comp Biochem Physiol C Comp Pharmacol Toxicol] 1986; Vol. 84 (2), pp. 359-61. - Publication Year :
- 1986
-
Abstract
- The extent of gastric damage induced by aspirin was found to differ according to rat strain. The occurrence of ulcers varied, from high to low, in the following strain order: Donryu, Sprague-Dawley (SD) and Wistar. The content of corpus mucus glycoprotein was essentially the same in all the strains: about 6 mg as hexose of dry tissue. Antral mucus glycoprotein content increased in the order Wistar, SD and Donryu: 7.1, 8.3 and 9.1 mg, respectively. Gastric mucus glycoprotein carbohydrate composition was essentially the same in all three strains. The relatively low proportions of N-acetylglucosamine, galactose and sialic acid from the antrum was a characteristic feature in contrast to mucus glycoprotein from the corpus which contained a high proportion of these sugars.
Details
- Language :
- English
- ISSN :
- 0742-8413
- Volume :
- 84
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology
- Publication Type :
- Academic Journal
- Accession number :
- 2874952
- Full Text :
- https://doi.org/10.1016/0742-8413(86)90105-2