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Asymptomatic choroidal tubercle in a patient with Crohn's disease on adalimumab treatment.

Authors :
Asensio-Sánchez VM
Díaz-Cabanas L
Martín-Prieto A
Haro-Álvarez B
Source :
Archivos de la Sociedad Espanola de Oftalmologia [Arch Soc Esp Oftalmol (Engl Ed)] 2018 Mar; Vol. 93 (3), pp. 147-150. Date of Electronic Publication: 2017 Jul 22.
Publication Year :
2018

Abstract

Introduction: Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection.<br />Case Report: The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study. Fluorescein angiography showed late hyperfluorescence in a staining pattern. Optic coherence tomography showed a flat mass without serous retinal detachment. The choroidal tubercle slowly regressed with antituberculosis therapy.<br />Discussion: Choroidal tubercles with no vitreo-retinal symptomatology can be present in patients with CD and on treatment with adalimumab.<br /> (Copyright © 2017 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.)

Details

Language :
English; Spanish; Castilian
ISSN :
2173-5794
Volume :
93
Issue :
3
Database :
MEDLINE
Journal :
Archivos de la Sociedad Espanola de Oftalmologia
Publication Type :
Academic Journal
Accession number :
28743416
Full Text :
https://doi.org/10.1016/j.oftal.2017.06.009