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Bilateral lesions of the paraventricular hypothalamic nucleus disrupt nursing behavior in rabbits.
- Source :
-
The European journal of neuroscience [Eur J Neurosci] 2017 Sep; Vol. 46 (5), pp. 2133-2140. Date of Electronic Publication: 2017 Aug 21. - Publication Year :
- 2017
-
Abstract
- Doe rabbits nurse the litter only once a day, for around 3 min, with circa 24-h periodicity. To explore the participation of the paraventricular nucleus (PVN) in regulating this behavior, we lesioned it bilaterally with kainic acid on lactation day 7. Bilateral lesions, comprising less than 50% of the total PVN volume, abolished nursing behavior (4/8 does) or severely disrupted its normal periodicity (4/8 does). In the latter case, duration of nursing bouts was normal. Body weight, food and water intake were not significantly affected by bilateral PVN lesions. Unilateral lesions of the PVN or lesions located outside this nucleus did not significantly alter nursing periodicity or any other behavioral parameter. Results indicate an important role of the PVN for (i) maintaining maternal behavior, and (ii) the periodic display of nursing across lactation in rabbits.<br /> (© 2017 The Authors. European Journal of Neuroscience published by Federation of European Neuroscience Societies and John Wiley & Sons Ltd.)
- Subjects :
- Actigraphy
Animals
Body Weight
Eating physiology
Female
Kainic Acid
Paraventricular Hypothalamic Nucleus pathology
Paraventricular Hypothalamic Nucleus physiopathology
Rabbits
Circadian Rhythm physiology
Lactation physiology
Maternal Behavior physiology
Paraventricular Hypothalamic Nucleus physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1460-9568
- Volume :
- 46
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The European journal of neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 28741792
- Full Text :
- https://doi.org/10.1111/ejn.13656