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Serologic Markers of Autism Spectrum Disorder.

Authors :
Khramova TV
Kaysheva AL
Ivanov YD
Pleshakova TO
Iourov IY
Vorsanova SG
Yurov YB
Schetkin AA
Archakov AI
Source :
Journal of molecular neuroscience : MN [J Mol Neurosci] 2017 Aug; Vol. 62 (3-4), pp. 420-429. Date of Electronic Publication: 2017 Jul 20.
Publication Year :
2017

Abstract

According to WHO data, about 67 million people worldwide are affected by autism, and this number grows by 14% annually. Among the possible causes of autism are genetic modifications, organic lesions of the central nervous system, metabolic disorders, influence of viral and bacterial infections, chemical influence to the mother's body during pregnancy, etc. The conducted research shows that research papers published until today do not name any potential protein markers that meet the requirements of the basic parameters for evaluating the efficiency of disease diagnostics, in particular high sensitivity, specificity, and accuracy. Conducting proteomic research on a big scale in order to detect serologic markers of protein nature associated with development of autism spectrum disorders seems to be highly relevant.

Details

Language :
English
ISSN :
1559-1166
Volume :
62
Issue :
3-4
Database :
MEDLINE
Journal :
Journal of molecular neuroscience : MN
Publication Type :
Academic Journal
Accession number :
28730336
Full Text :
https://doi.org/10.1007/s12031-017-0950-9