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Palladium-catalyzed dearomatizative [2 + 2 + 1] carboannulation of 1,7-enynes with aryl diazonium salts and H 2 O: facile synthesis of spirocyclohexadienone-fused cyclopenta[c]quinolin-4(5H)-ones.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2017 Jul 27; Vol. 53 (61), pp. 8600-8603. - Publication Year :
- 2017
-
Abstract
- A new palladium-catalyzed dearomatizative [2 + 2 + 1] carboannulation of 1,7-enynes with aryl diazonium salts and H <subscript>2</subscript> O is presented. The reaction enables the construction of spirocyclohexadienone-fused cyclopenta[c]quinolin-4(5H)-ones through a sequence of Heck-type addition, 6-exo-dig cyclization, ipso-cyclization, dearomatization and hydrolysis.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 53
- Issue :
- 61
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 28718484
- Full Text :
- https://doi.org/10.1039/c7cc02830j