Zinc-promoted cyclization of tosylhydrazones and 2-(dimethylamino)malononitrile: an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.

Authors :: Zhang BH
Lei LS
Liu SZ
Mou XQ
Liu WT
Wang SH
Wang J
Bao W
Zhang K
Source :: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2017 Jul 27; Vol. 53 (61), pp. 8545-8548.
Publication Year :: 2017
Abstract: A Zn(OTf) <subscript>2</subscript> -promoted cyclization reaction of tosylhydrazones with 2-(dimethylamino)malononitrile has been successfully developed providing an efficient strategy for the synthesis of substituted 1-tosyl-1H-pyrazoles.

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