High performance modelling of the transport of energetic particles for photon radiotherapy.

Authors :: Birindelli G
Feugeas JL
Caron J
Dubroca B
Kantor G
Page J
Pichard T
Tikhonchuk V
Nicolaï P
Source :: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [Phys Med] 2017 Oct; Vol. 42, pp. 305-312. Date of Electronic Publication: 2017 Jun 30.
Publication Year :: 2017
Abstract: This work consists of the validation of a new Grid Based Boltzmann Solver (GBBS) conceived for the description of the transport and energy deposition by energetic particles for radiotherapy purposes. The entropic closure and a compact mathematical formulation allow our code (M1) to calculate the delivered dose with an accuracy comparable to the Monte-Carlo (MC) codes with a computational time that is reduced to the order of few minutes without any special processing power requirement. A validation protocol with heterogeneity inserts has been defined for different photon sources. The comparison with the MC calculated depth-dose curves and transverse profiles of the beam at different depths shows an excellent accuracy of the M1 model.<br /> (Copyright © 2017 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.)

Subjects :: Algorithms
Computer Simulation
Humans
Monte Carlo Method
Radiometry instrumentation
Radiotherapy Dosage
Water
Models, Theoretical
Photons therapeutic use
Radiotherapy Planning, Computer-Assisted methods

Language :: English
ISSN :: 1724-191X
Volume :: 42
Database :: MEDLINE
Journal :: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Publication Type :: Academic Journal
Accession number :: 28673482
Full Text :: https://doi.org/10.1016/j.ejmp.2017.06.020

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