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Mortality Among Hardmetal Production Workers: A Retrospective Cohort Study in the Austrian Hardmetal Industry.
- Source :
-
Journal of occupational and environmental medicine [J Occup Environ Med] 2017 Dec; Vol. 59 (12), pp. e282-e287. - Publication Year :
- 2017
-
Abstract
- Objective: This study retrospectively investigates causes of death among workers of a hardmetal plant in Austria.<br />Methods: A retrospective cohort was formed of 1965 workers still employed in or after 1970. Follow-up was until end of 2014 based on national databases. Cobalt exposure was assessed through industrial hygiene data and urine analyses. Cox proportional hazards models were calculated for selected causes of death.<br />Results: During 45,598 years of observation in total 177 deaths were observed. Forty-nine workers died from any cancer, 10 from lung cancer, and three from chronic obstructive pulmonary disease. Only the latter showed a significant association with cumulative exposure.<br />Conclusions: Although this is a young study population with little power to detect subtle effects, at least it does not indicate a pronounced cancer risk among tungsten carbide workers due to cobalt.
- Subjects :
- Austria
Cause of Death
Cohort Studies
Databases, Factual
Female
Follow-Up Studies
Humans
Lung Neoplasms chemically induced
Male
Occupational Exposure statistics & numerical data
Proportional Hazards Models
Retrospective Studies
Risk Factors
Survival Analysis
Alloys adverse effects
Chemical Industry statistics & numerical data
Cobalt adverse effects
Lung Neoplasms mortality
Occupational Diseases mortality
Occupational Exposure adverse effects
Tungsten adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1536-5948
- Volume :
- 59
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Journal of occupational and environmental medicine
- Publication Type :
- Academic Journal
- Accession number :
- 28665836
- Full Text :
- https://doi.org/10.1097/JOM.0000000000001046