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Hepatic expression of cytochrome P450 enzymes in non-human primate species.

Authors :
Uehara S
Uno Y
Yamazaki H
Source :
Journal of medical primatology [J Med Primatol] 2017 Dec; Vol. 46 (6), pp. 347-351. Date of Electronic Publication: 2017 Jun 29.
Publication Year :
2017

Abstract

Cytochromes P450 (P450) largely remain to be characterized in great apes. Comparative immunochemical detection of drug metabolizing forms of P450s 1A, 2A, 2B, 2C, 2D, 2E, 2J, 3A, 4A, and 4F in liver microsomes from chimpanzees, gorillas, orangutans, gibbons, cynomolgus and rhesus macaques, and common marmosets were carried out.<br /> (© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)

Details

Language :
English
ISSN :
1600-0684
Volume :
46
Issue :
6
Database :
MEDLINE
Journal :
Journal of medical primatology
Publication Type :
Academic Journal
Accession number :
28664555
Full Text :
https://doi.org/10.1111/jmp.12288