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Unique Imaging Features Enabling the Prenatal Diagnosis of Developmental Venous Anomalies: A Persistent Echogenic Brain Lesion Drained by a Collecting Vein in Contrast with Normal Brain Parenchyma on MRI.
- Source :
-
Fetal diagnosis and therapy [Fetal Diagn Ther] 2018; Vol. 43 (1), pp. 53-60. Date of Electronic Publication: 2017 Jun 17. - Publication Year :
- 2018
-
Abstract
- Objective: To describe the prenatal imaging features enabling diagnosis of developmental venous anomalies (DVA).<br />Methods: Four fetuses with unexplained persistent echogenic parenchymal brain lesions were studied. The evaluation included dedicated neurosonography, fetal MRI, serology for intrauterine infection, screening for coagulation abnormalities, and chromosomal microarray. Postnatal neurodevelopmental follow-up or autopsy results were assessed.<br />Results: DVA presented as very slowly growing echogenic brain lesions without cystic components, calcifications, or structural changes on otherwise normal neurosonographic scans performed at 2- to 3-week intervals. A specific Doppler feature was a collecting vein draining the echogenic parenchyma. Fetal brain MRI depicted normal anatomy on half-Fourier acquisition single-shot turbo spin-echo and diffusion-weighted imaging. The rest of the evaluation was normal.<br />Conclusions: In cases with a persistent, parenchymal echogenic lesion without clastic or structural changes, DVA should be considered. Demonstration of a collecting vein draining the lesion and normal brain anatomy on MRI confirm the diagnosis.<br /> (© 2017 S. Karger AG, Basel.)
- Subjects :
- Abortion, Induced
Adult
Age Factors
Autopsy
Central Nervous System Vascular Malformations pathology
Cerebral Veins abnormalities
Cerebral Veins pathology
Child Development
Female
Gestational Age
Humans
Infant
Predictive Value of Tests
Pregnancy
Prognosis
Reproducibility of Results
Central Nervous System Vascular Malformations diagnostic imaging
Cerebral Veins diagnostic imaging
Magnetic Resonance Imaging
Parenchymal Tissue diagnostic imaging
Ultrasonography, Doppler, Transcranial
Ultrasonography, Prenatal methods
Subjects
Details
- Language :
- English
- ISSN :
- 1421-9964
- Volume :
- 43
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Fetal diagnosis and therapy
- Publication Type :
- Academic Journal
- Accession number :
- 28624828
- Full Text :
- https://doi.org/10.1159/000464247