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[Find your way in the jungle of mAbs].
- Source :
-
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine [Transfus Clin Biol] 2017 Sep; Vol. 24 (3), pp. 216-217. Date of Electronic Publication: 2017 Jun 12. - Publication Year :
- 2017
-
Abstract
- The rapidly increasing number of approved monoclonal antibodies (mAbs) and the huge number of mAbs in clinical development are a matter of concern for who wants to easily identify targets, indications, mechanisms of action and possible adverse effects. The current nomenclature being of limited interest, simple rationales will be presented for helping practitioners in rapidly classify mAbs depending on their structure-pharmacology relationship and in evaluating their potential effects, particularly in transfusion medicine.<br /> (Copyright © 2017 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Antibodies, Monoclonal classification
Antibodies, Monoclonal immunology
Antibodies, Neutralizing immunology
Antibody Specificity
Antigen-Antibody Reactions
Antigens, Surface immunology
Blood Transfusion
Erythrocytes immunology
Humans
Immunoglobulin G classification
Immunoglobulin G immunology
Leukocytes immunology
Molecular Targeted Therapy
Protein Engineering
Antibodies, Monoclonal therapeutic use
Subjects
Details
- Language :
- French
- ISSN :
- 1953-8022
- Volume :
- 24
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
- Publication Type :
- Academic Journal
- Accession number :
- 28619531
- Full Text :
- https://doi.org/10.1016/j.tracli.2017.05.008