Introduction to Metals in Biology 2017: Iron transport, storage, and the ramifications.

In this tenth Thematic Series in Metals in Biology, six Minireviews deal with aspects of iron metabolism. A number of important proteins control iron homeostasis, including hepcidin and ferroportin, in various cells. Other aspects of iron dealt with here include biogenesis of iron-sulfur proteins and chaperones that deliver iron cofactors in cells. Additionally, an iron-regulated metastasis suppressor interacts with the epidermal growth factor receptor and mediates its downstream signaling activity.
Competing Interests: The author declares that he has no conflicts of interest with the contents of this article.
(© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.)