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Cell surface glycoprotein analysis: a diagnostic tool in human leukemias.
- Source :
-
International journal of cancer [Int J Cancer] 1979 Mar 15; Vol. 23 (3), pp. 306-11. - Publication Year :
- 1979
-
Abstract
- We have radiolabelled surface glycoproteins of different types of leukemic cell. The labelled proteins were separated by polyacrylamide slab gel electrophoresis and visualized by fluorography. Surface glycoprotein patterns discriminatory for acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) were found. We conclude that the analysis of the surface glycoprotein profile provides a useful method for the classification of leukemic cells according to cell type and stage of differentiation.
- Subjects :
- Adult
Aged
Cell Separation
Child
Child, Preschool
Diagnosis, Differential
Electrophoresis, Polyacrylamide Gel
Female
Granulocytes analysis
Humans
Leukemia blood
Leukemia, Lymphoid diagnosis
Leukemia, Myeloid diagnosis
Leukemia, Myeloid, Acute diagnosis
Male
Middle Aged
Glycoproteins blood
Leukemia diagnosis
Leukocytes analysis
Membrane Proteins blood
Subjects
Details
- Language :
- English
- ISSN :
- 0020-7136
- Volume :
- 23
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- International journal of cancer
- Publication Type :
- Academic Journal
- Accession number :
- 285925
- Full Text :
- https://doi.org/10.1002/ijc.2910230306