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Bilateral acute retinal necrosis after bilateral cataract surgery in an immunocompromised patient: a case report.
- Source :
-
International ophthalmology [Int Ophthalmol] 2018 Jun; Vol. 38 (3), pp. 1329-1332. Date of Electronic Publication: 2017 May 23. - Publication Year :
- 2018
-
Abstract
- Purpose: To report a case of bilateral varicella zoster virus (VZV)-associated acute retinal necrosis (ARN) occurring after both eyes sequential cataract surgery in an elderly immunocompromised patient.<br />Methods: Medical records and investigation results of the patient were reviewed.<br />Results: Patient experienced floaters and blurring of vision in both eyes 4 weeks after her second uncomplicated cataract surgery. Clinical signs of granulomatous keratic precipitates, prominent vitritis, retinitis and vascular thrombosis were noted in both eyes. Aqueous samples from both eyes were positive for VZV. Disease was treated with intravitreal foscarnet bilaterally and 10 days of systemic intravenous acyclovir (10 mg/kg) followed by oral valaciclovir 1 g three times daily. Final visual acuity at 4 months after initial presentation was 20/60 in both eyes with no retinal detachment noted.<br />Conclusions: Cataract surgery may have been the trigger for bilateral VZV-associated ARN. Immunocompromised patients can develop ARN and require close observation after cataract surgery. This is, to our knowledge, the first report of bilateral ARN following routine cataract surgery.
- Subjects :
- Aged
Antibodies, Viral immunology
Eye Infections, Viral virology
Female
Humans
Retinal Necrosis Syndrome, Acute immunology
Retinal Necrosis Syndrome, Acute virology
Surgical Wound Infection immunology
Surgical Wound Infection virology
Varicella Zoster Virus Infection diagnosis
Varicella Zoster Virus Infection virology
Visual Acuity
Cataract Extraction adverse effects
Eye Infections, Viral etiology
Herpesvirus 3, Human immunology
Immunocompromised Host
Retinal Necrosis Syndrome, Acute etiology
Surgical Wound Infection etiology
Varicella Zoster Virus Infection etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1573-2630
- Volume :
- 38
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- International ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 28536762
- Full Text :
- https://doi.org/10.1007/s10792-017-0555-x