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Multiphysics Modeling of the Atrial Systole under Standard Ablation Strategies.

Multiphysics Modeling of the Atrial Systole under Standard Ablation Strategies.

Authors :
Hörmann JM
Bertoglio C
Nagler A
Pfaller MR
Bourier F
Hadamitzky M
Deisenhofer I
Wall WA
Source :
Cardiovascular engineering and technology [Cardiovasc Eng Technol] 2017 Jun; Vol. 8 (2), pp. 205-218. Date of Electronic Publication: 2017 May 16.
Publication Year :
2017

Abstract

The aim of this study was to develop a computational framework to compare the impact of standard ablation concepts on the mechanical performance of the atria, since different line combinations cannot be applied in practice to the same patient. For this purpuse, we coupled electro-mechano-hemodynamic mathematical models based on biophysical principles and simulate the contractile performance of the atria. We computed systolic pressures and volumes in two patient-specific atrial geometries (one of normal size and one hypertrophied) with various ablation concepts. We found that our computational model is able to detect the differences in the left atrial contractility and ejection fraction for various electrical activation sequences resulting from different ablation line combinations. We show that multiphysics modeling has the potential to quantify the hemodynamic performance of left atria for different ablation lines, which could be used as additional pre-operative clinical information for the choice of the ablation concept in the future.

Details

Language :
English
ISSN :
1869-4098
Volume :
8
Issue :
2
Database :
MEDLINE
Journal :
Cardiovascular engineering and technology
Publication Type :
Academic Journal
Accession number :
28512679
Full Text :
https://doi.org/10.1007/s13239-017-0308-z