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Presence and Predictive Value of Obsessive-Compulsive Symptoms in Anxiety and Depressive Disorders.
- Source :
-
Canadian journal of psychiatry. Revue canadienne de psychiatrie [Can J Psychiatry] 2018 Feb; Vol. 63 (2), pp. 85-93. Date of Electronic Publication: 2017 May 16. - Publication Year :
- 2018
-
Abstract
- Objective: Obsessive-compulsive symptoms (OCS) co-occur frequently with anxiety and depressive disorders, but the nature of their relationship and their impact on severity of anxiety and depressive disorders is poorly understood. In a large sample of patients with anxiety and depressive disorders, we assessed the frequency of OCS, defined as a Young Adult Self-Report Scale-obsessive-compulsive symptoms score >7. The associations between OCS and severity of anxiety and/or depressive disorders were examined, and it was investigated whether OCS predict onset, relapse, and persistence of anxiety and depressive disorders.<br />Methods: Data were obtained from the third (at 2-year follow-up) and fourth wave (at 4-year follow-up) of data collection in the Netherlands Study of Anxiety and Depression cohort, including 469 healthy controls, 909 participants with a remitted disorder, and 747 participants with a current anxiety and/or depressive disorder.<br />Results: OCS were present in 23.6% of the total sample, most notably in those with current combined anxiety and depressive disorders. In patients with a current disorder, OCS were associated with severity of this disorder. Moreover, OCS predicted (1) first onset of anxiety and/or depressive disorders in healthy controls (odds ratio [OR], 5.79; 95% confidence interval [CI], 1.15 to 29.14), (2) relapse in those with remitted anxiety and/or depressive disorders (OR, 2.31; 95% CI, 1.55 to 3.46), and (3) persistence in patients with the combination of current anxiety and depressive disorders (OR, 4.42; 95% CI, 2.54 to 7.70) within the 2-year follow-up period Conclusions: OCS are closely related to both the presence and severity of anxiety and depressive disorders and affect their course trajectories. Hence, OCS might be regarded as a course specifier signaling unfavorable outcomes. This specifier may be useful in clinical care to adapt and intensify treatment in individual patients.
- Subjects :
- Adult
Anxiety Disorders diagnosis
Anxiety Disorders physiopathology
Comorbidity
Depressive Disorder diagnosis
Depressive Disorder physiopathology
Female
Follow-Up Studies
Humans
Male
Middle Aged
Netherlands epidemiology
Obsessive-Compulsive Disorder diagnosis
Obsessive-Compulsive Disorder physiopathology
Prevalence
Prognosis
Severity of Illness Index
Anxiety Disorders epidemiology
Depressive Disorder epidemiology
Obsessive-Compulsive Disorder epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1497-0015
- Volume :
- 63
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Canadian journal of psychiatry. Revue canadienne de psychiatrie
- Publication Type :
- Academic Journal
- Accession number :
- 28511595
- Full Text :
- https://doi.org/10.1177/0706743717711170