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Peripheral arteriovenous fistula as vascular access for long-term chemotherapy.
- Source :
-
Wiadomosci lekarskie (Warsaw, Poland : 1960) [Wiad Lek] 2017; Vol. 70 (2), pp. 165-168. - Publication Year :
- 2017
-
Abstract
- Introduction: To provide long-term vascular access in clinical oncology peripheral forearm veins (up to 95% of patients in Ukraine), central venous access and "complete implanted vascular systems" are used most often. Many oncology patients have contraindications to catheterization of superior vena cava. Besides, exploitation of central veins is associated with potential technical and infectious complications. The aim - to study short-term and long-term results of arteriovenous fistula exploitation as vascular access for continuous anticancer therapy.<br />Materials and Methods: Peripheral venous bed status in 41 oncology patients taking long-term chemotherapy treatment is analyzed in the article. Doppler sonography, morphologic and immune histochemical analyses were used in the study.<br />Results: Doppler sonography found qualitative and quantitative changes in forearm veins at different time periods after initiation of chemotherapy in the majority of patients. The major morphologic manifestations of venous wall damage were chemical phlebitis, local or extended hardening of venous wall, venous thrombosis and extravasations with necrosis and subsequent paravasal tissue sclerosis. Alternative vascular access created in 12 patients completely met the adequacy criteria (safety, multiple use, longevity, realization of the designed therapy program). The conclusion was made about inapplicability of forearm veins for long-term administration of cytostatic agents. If it is impossible to use central veins, arteriovenous fistula can become an alternative vascular access.
- Subjects :
- Adult
Antineoplastic Agents adverse effects
Antineoplastic Agents therapeutic use
Extravasation of Diagnostic and Therapeutic Materials etiology
Extravasation of Diagnostic and Therapeutic Materials pathology
Female
Forearm blood supply
Humans
Male
Middle Aged
Patient Safety
Ultrasonography, Doppler
Veins pathology
Venous Thrombosis etiology
Venous Thrombosis pathology
Antineoplastic Agents administration & dosage
Arteriovenous Fistula
Infusions, Intravenous adverse effects
Long-Term Care
Neoplasms drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0043-5147
- Volume :
- 70
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Wiadomosci lekarskie (Warsaw, Poland : 1960)
- Publication Type :
- Academic Journal
- Accession number :
- 28511151