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Two new compounds from the fruiting bodies of Ganoderma philippii.
- Source :
-
Journal of Asian natural products research [J Asian Nat Prod Res] 2018 Mar; Vol. 20 (3), pp. 249-254. Date of Electronic Publication: 2017 May 16. - Publication Year :
- 2018
-
Abstract
- Two new compounds, philippin (1) and 3β,9α,14α-trihydroxy-(22E,24R)-ergost-22-en-7-one (2), were isolated from the fruiting bodies of Ganoderma philippii. Their structures were elucidated on the basis of the spectroscopic technologies, including 1D and 2D NMR as well as MS. The bioassay of inhibitory activity against acetylcholinesterase (AChE) showed compound 1 exhibited weak inhibitory activity against AChE.
- Subjects :
- Acetylcholinesterase drug effects
Cholinesterase Inhibitors chemistry
Cholinesterase Inhibitors pharmacology
Ergosterol chemistry
Ergosterol isolation & purification
Fruiting Bodies, Fungal chemistry
Hydroquinones chemistry
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Cholinesterase Inhibitors isolation & purification
Ergosterol analogs & derivatives
Ganoderma chemistry
Hydroquinones isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1477-2213
- Volume :
- 20
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of Asian natural products research
- Publication Type :
- Academic Journal
- Accession number :
- 28508676
- Full Text :
- https://doi.org/10.1080/10286020.2017.1326911