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Liver-to-abdominal area ratio for predicting the in-hospital mortality in advanced liver cirrhosis.
- Source :
-
Postgraduate medicine [Postgrad Med] 2017 Sep; Vol. 129 (7), pp. 756-761. Date of Electronic Publication: 2017 May 19. - Publication Year :
- 2017
-
Abstract
- Objectives: To identify the value of liver-to-abdominal area ratio (LAAR) score for predicting the in-hospital mortality in advanced cirrhotic patients.<br />Methods: All cirrhotic patients with Child-Pugh class B or C who were admitted between July 2012 and June 2014 and underwent abdominopelvic CT scans were considered in this retrospective observational study. The association of LAAR with in-hospital death was calculated. Receiver operating characteristic curve analysis was performed. The area under curve (AUC) was calculated.<br />Results: In the overall analysis of 128 cirrhotic patients with Child-Pugh class B or C, LAAR score was significantly associated with the risk of in-hospital death (p = 0.012). The AUC of LAAR score for predicting the in-hospital mortality was 0.764 (p < 0.0001). The best cut-off value was 0.29 with a sensitivity of 75% and a specificity of 73.33%. In the subgroup analysis of 37 patients with Child-Pugh class C, LAAR score was significantly associated with the risk of in-hospital death (p = 0.008). The AUC of LAAR score was 0.821. The best cut-off value was 0.29 with a sensitivity of 85.71% and a specificity of 80%. In the subgroup analysis of 80 patients with moderate-severe ascites, LAAR score was not significantly associated with the risk of in-hospital death (p = 0.072). The AUC of LAAR score was 0.684 (p = 0.0158). The best cut-off value was 0.29 with a sensitivity of 75% and a specificity of 63.89%.<br />Conclusion: LAAR score might be effective for predicting the in-hospital death of advanced cirrhosis.
- Subjects :
- Adult
Aged
Aged, 80 and over
Female
Health Status Indicators
Hospital Mortality
Humans
Male
Middle Aged
Predictive Value of Tests
Retrospective Studies
Risk Assessment
Risk Factors
Sensitivity and Specificity
Severity of Illness Index
Abdomen anatomy & histology
Liver anatomy & histology
Liver Cirrhosis mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1941-9260
- Volume :
- 129
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Postgraduate medicine
- Publication Type :
- Academic Journal
- Accession number :
- 28486857
- Full Text :
- https://doi.org/10.1080/00325481.2017.1327781