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Liver-to-abdominal area ratio for predicting the in-hospital mortality in advanced liver cirrhosis.

Authors :
Gao F
Wang R
Deng H
Hou F
Romeiro FG
Qi X
Source :
Postgraduate medicine [Postgrad Med] 2017 Sep; Vol. 129 (7), pp. 756-761. Date of Electronic Publication: 2017 May 19.
Publication Year :
2017

Abstract

Objectives: To identify the value of liver-to-abdominal area ratio (LAAR) score for predicting the in-hospital mortality in advanced cirrhotic patients.<br />Methods: All cirrhotic patients with Child-Pugh class B or C who were admitted between July 2012 and June 2014 and underwent abdominopelvic CT scans were considered in this retrospective observational study. The association of LAAR with in-hospital death was calculated. Receiver operating characteristic curve analysis was performed. The area under curve (AUC) was calculated.<br />Results: In the overall analysis of 128 cirrhotic patients with Child-Pugh class B or C, LAAR score was significantly associated with the risk of in-hospital death (p = 0.012). The AUC of LAAR score for predicting the in-hospital mortality was 0.764 (p < 0.0001). The best cut-off value was 0.29 with a sensitivity of 75% and a specificity of 73.33%. In the subgroup analysis of 37 patients with Child-Pugh class C, LAAR score was significantly associated with the risk of in-hospital death (p = 0.008). The AUC of LAAR score was 0.821. The best cut-off value was 0.29 with a sensitivity of 85.71% and a specificity of 80%. In the subgroup analysis of 80 patients with moderate-severe ascites, LAAR score was not significantly associated with the risk of in-hospital death (p = 0.072). The AUC of LAAR score was 0.684 (p = 0.0158). The best cut-off value was 0.29 with a sensitivity of 75% and a specificity of 63.89%.<br />Conclusion: LAAR score might be effective for predicting the in-hospital death of advanced cirrhosis.

Details

Language :
English
ISSN :
1941-9260
Volume :
129
Issue :
7
Database :
MEDLINE
Journal :
Postgraduate medicine
Publication Type :
Academic Journal
Accession number :
28486857
Full Text :
https://doi.org/10.1080/00325481.2017.1327781