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Using Epigenetic Reprogramming to Treat Pediatric Brain Cancer.
- Source :
-
Cancer cell [Cancer Cell] 2017 May 08; Vol. 31 (5), pp. 609-611. - Publication Year :
- 2017
-
Abstract
- In this issue of Cancer Cell, Nagaraja et al. dissect the molecular mechanisms underlying therapeutic responses to transcriptional disruptors in the fatal pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG). Moreover, they identify super-enhancers mediating these effects, highlighting how normal brain developmental programs can be hijacked in cancer.<br /> (Copyright © 2017 Elsevier Inc. All rights reserved.)
- Subjects :
- Brain
Child
Epigenomics
Humans
Brain Stem Neoplasms
Glioma
Subjects
Details
- Language :
- English
- ISSN :
- 1878-3686
- Volume :
- 31
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Cancer cell
- Publication Type :
- Academic Journal
- Accession number :
- 28486100
- Full Text :
- https://doi.org/10.1016/j.ccell.2017.04.008