Influence of ofloxacin and pefloxacin on human lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production.

Authors :: Fantoni M
Tamburrini E
Pallavicini F
Antinori A
Nervo P
Source :: The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 1988 Aug; Vol. 22 (2), pp. 193-6.
Publication Year :: 1988
Abstract: The influence of two fluoroquinolone derivatives, ofloxacin and pefloxacin, on lymphocyte immunoglobulin secretion and on polymorphonuclear leucocyte superoxide anion production was assessed. Pharmacological concentrations did not influence the studied functions, while suprapharmacological concentrations decreased immunoglobulin production.

Subjects :: Humans
Superoxides metabolism
Immunoglobulin G metabolism
Lymphocytes immunology
Neutrophils metabolism
Ofloxacin pharmacology
Pefloxacin pharmacology

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