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Fundus findings in a series of patients with extrapulmonary tuberculosis in Thailand.

Authors :
Jirawison C
Liu Y
Surasit K
Maningding E
Kamphaengkham S
Ausayakhun S
Heiden D
Margolis TP
Gonzales JA
Acharya NR
Keenan JD
Source :
The British journal of ophthalmology [Br J Ophthalmol] 2017 Jun; Vol. 101 (6), pp. 691-694. Date of Electronic Publication: 2017 Apr 27.
Publication Year :
2017

Abstract

Aim: The aim of this study was to determine the frequency of fundus abnormalities among patients who are undergoing or have recently completed treatment for extrapulmonary tuberculosis (eTB).<br />Methods: This is a prospective cross-sectional study conducted in a TB clinic of a tertiary hospital in northern Thailand. All patients who had eTB between January 2014 and August 2015 were invited by telephone to return to the clinic for fundus photography. Three uveitis specialists reviewed all photographs to identify posterior segment lesions that were consistent with ocular TB.<br />Results: A total of 265 patients were diagnosed with eTB during the specified period, of which 118 (44.5%) were reached by telephone and 60 (50.8%) participated in the study. A total of 7 eyes from six patients (10.0% of participants, 95% CI 2.2% to 17.8%) had lesions consistent with ocular TB. The group with possible ocular TB lesions was on average 16.8 years older than those without ocular lesions (p=0.01), but the two groups were otherwise not significantly different.<br />Conclusion: Ocular lesions consistent with TB were not rare in a group of patients who were undergoing or had recently completed treatment for eTB. Fundus examination may provide diagnostic information that could influence a clinician's beliefs when diagnosing eTB. Given the low costs and immediate results of eye examination, this diagnostic test should be considered in patients suspected for eTB, especially when other tests are negative.<br />Competing Interests: Competing interests: None declared.<br /> (© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)

Details

Language :
English
ISSN :
1468-2079
Volume :
101
Issue :
6
Database :
MEDLINE
Journal :
The British journal of ophthalmology
Publication Type :
Academic Journal
Accession number :
28450377
Full Text :
https://doi.org/10.1136/bjophthalmol-2016-310105