Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? T-Cell Heterogeneity, Plasticity, and Selection in Humans.

Authors :: Sallusto F
Cassotta A
Hoces D
Foglierini M
Lanzavecchia A
Source :: Cold Spring Harbor perspectives in biology [Cold Spring Harb Perspect Biol] 2018 Mar 01; Vol. 10 (3). Date of Electronic Publication: 2018 Mar 01.
Publication Year :: 2018
Abstract: The wide range of effector and memory T cells is instrumental for immune regulation and tailored mechanisms of protection against pathogens. Here, we will focus on human CD4 T cells and discuss T-cell plasticity and intraclonal diversification in the context of a progressive and selective model of CD4 T-cell differentiation.<br /> (Copyright © 2018 Cold Spring Harbor Laboratory Press; all rights reserved.)

Subjects :: CD4-Positive T-Lymphocytes immunology
Cell Differentiation
Cellular Reprogramming
Humans
CD4-Positive T-Lymphocytes physiology
Cell Plasticity
Immunologic Memory

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