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Computed tomography of mediastinal lymph nodes in nonsmall cell lung cancer. A new approach based on the lymphatic pathway of tumor spread.
- Source :
-
Journal of computer assisted tomography [J Comput Assist Tomogr] 1988 Jul-Aug; Vol. 12 (4), pp. 545-52. - Publication Year :
- 1988
-
Abstract
- Computed tomography was used to evaluate mediastinal lymph nodes in 97 patients with nonsmall cell lung cancer. All patients had thorough surgical-pathological determination of mediastinal node status. Twenty-three patients were found to have metastatic lymph nodes. The usual lymphatic pathways of tumor spread into the mediastinum were defined using the node mapping scheme suggested by the American Thoracic Society. We considered mediastinal nodes abnormal when the short axis of the largest mediastinal node in the lymphatic drainage territory of the cancer was greater than or equal to 10 mm and the difference between this node and the largest node in the other territories is greater than 5 mm. The sensitivity was 78%, the specificity 99%, the positive predictive value 95%, the negative predictive value 94%, and the accuracy 94%. Comparing our method to those that used the size criterion alone, the number of false positives was reduced.
- Subjects :
- Adult
Aged
Carcinoma, Bronchogenic pathology
Carcinoma, Non-Small-Cell Lung pathology
Female
Humans
Lung Neoplasms pathology
Lymph Nodes pathology
Male
Mediastinum
Middle Aged
Carcinoma, Bronchogenic diagnostic imaging
Carcinoma, Non-Small-Cell Lung diagnostic imaging
Lung Neoplasms diagnostic imaging
Lymph Nodes diagnostic imaging
Lymphatic Metastasis diagnostic imaging
Tomography, X-Ray Computed
Subjects
Details
- Language :
- English
- ISSN :
- 0363-8715
- Volume :
- 12
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of computer assisted tomography
- Publication Type :
- Academic Journal
- Accession number :
- 2839559
- Full Text :
- https://doi.org/10.1097/00004728-198807000-00001