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Nanotechnology application to local anaesthesia (LA).

Authors :
Moradkhani MR
Karimi A
Negahdari B
Source :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2018 Mar; Vol. 46 (2), pp. 355-360. Date of Electronic Publication: 2017 Apr 10.
Publication Year :
2018

Abstract

Several advancements have been made on the exact release of local anaesthetics formulation and its efficiency at inducing motor and sensory block for an extended time has been harnessed in clinical practice. The use of sustained release formulations delivers analgesia for a lengthier period of time with one administration, thereby reducing complications that usually arise with administration of conventional analgesia. In addition, controlled release of an anaesthetic drug is said to prevent overdosing, reduced side effects, especially cardiotoxicity, neurotoxicity and tissue lesions. The use of nanotechnology knowledge via liposomal formulation has recorded high successful results in pain control and quick patient recovery.

Details

Language :
English
ISSN :
2169-141X
Volume :
46
Issue :
2
Database :
MEDLINE
Journal :
Artificial cells, nanomedicine, and biotechnology
Publication Type :
Academic Journal
Accession number :
28395522
Full Text :
https://doi.org/10.1080/21691401.2017.1313263