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Iron Mapping in Multiple Sclerosis.
- Source :
-
Neuroimaging clinics of North America [Neuroimaging Clin N Am] 2017 May; Vol. 27 (2), pp. 335-342. Date of Electronic Publication: 2017 Jan 20. - Publication Year :
- 2017
-
Abstract
- Increased iron deposition in cerebral deep gray matter has been considered a global marker for neurodegeneration in multiple sclerosis (MS); it scales with disease duration and severity. Iron accumulation in white matter and MS lesions might be more directly related to disease activity and has been discussed as a contributor to the inflammatory and neurodegenerative cascade. New insights into iron and MS are expected from MR imaging. We discuss findings from MR iron mapping proposed. Because of the confounding magnetic properties of myelin, iron mapping in white matter remains an unresolved issue.<br /> (Copyright © 2016 Elsevier Inc. All rights reserved.)
Details
- Language :
- English
- ISSN :
- 1557-9867
- Volume :
- 27
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Neuroimaging clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 28391790
- Full Text :
- https://doi.org/10.1016/j.nic.2016.12.003