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Synthesis and characterization of Bioglass-based bone grafts with Gelatine substitution for biomedical applications.
- Source :
-
Bio-medical materials and engineering [Biomed Mater Eng] 2017; Vol. 28 (2), pp. 159-168. - Publication Year :
- 2017
-
Abstract
- Background: Syntesizing alternative bone graft materials are important in biomedical applications. Their morphology, mechanical properties and cell viability plays an important role in tissue engineering.<br />Objective: Bioglass (B) based bone grafts with Gelatin (G) substitution were syntesized via the sol-gel method and were compared with various Gelatin and Bioglass concentrations (wt%).<br />Methods: Syntesized bone grafts were characterized by Scanning Electron Microscopy (SEM) and X-ray diffraction (XRD) to show the structural and morphological changes of the fabricated B-based bone grafts.<br />Results: It was demonstrated that the concentration of pore size increased with increasing amounts of Gelatin in wt%. The biograft-B40G20 produced the highest flexture strength and hardness. Increasing the pore size caused a decrease in hardness and flexture stress of B-based biografts.<br />Conclusions: Cell viability tests were conducted on the fabricated biografts and it was shown that the cell viability increased in fabricated B-based bone grafts.
Details
- Language :
- English
- ISSN :
- 1878-3619
- Volume :
- 28
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Bio-medical materials and engineering
- Publication Type :
- Academic Journal
- Accession number :
- 28372268
- Full Text :
- https://doi.org/10.3233/BME-171664