Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses.

Authors :: Leentjens J
Gresnigt MS
van de Veerdonk FL
Kox M
Kullberg BJ
Pickkers P
Brouwer AE
Netea MG
Source :: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2017 Jun; Vol. 59, pp. 25-28. Date of Electronic Publication: 2017 Mar 22.
Publication Year :: 2017
Abstract: Despite advances in medical care, mortality due to cerebral Nocardia abscesses remains unacceptably high. The case of a typical immunocompromised patient, who deteriorated clinically despite optimal antimicrobial treatment, is reported here. Adjuvant immunotherapy with interferon-gamma resulted in partial restoration of the immune response and a corresponding clinical and radiographic recovery.<br /> (Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Subjects :: Adjuvants, Immunologic therapeutic use
Brain Abscess diagnostic imaging
Brain Abscess microbiology
Humans
Immunocompromised Host
Magnetic Resonance Imaging
Male
Middle Aged
Nocardia Infections microbiology
Antiviral Agents administration & dosage
Brain Abscess drug therapy
Interferon-gamma therapeutic use
Nocardia
Nocardia Infections diagnostic imaging
Nocardia Infections drug therapy

Language :: English
ISSN :: 1878-3511
Volume :: 59
Database :: MEDLINE
Journal :: International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Publication Type :: Academic Journal
Accession number :: 28342802
Full Text :: https://doi.org/10.1016/j.ijid.2017.03.013

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