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Echinodorus grandiflorus: Ethnobotanical, phytochemical and pharmacological overview of a medicinal plant used in Brazil.
- Source :
-
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2017 Nov; Vol. 109 (Pt 2), pp. 1032-1047. Date of Electronic Publication: 2017 Mar 18. - Publication Year :
- 2017
-
Abstract
- Echinodorus grandiflorus (Cham. & Schltdl.) Micheli is a native Brazilian species used in traditional practices for the treatment of several conditions such as inflammatory diseases, arthritis and hypertension. Through a systematic review of the accumulated knowledge about the species E. grandiflorus, the botanical, phytochemistry, ethnobotanical and pharmacological properties of this medicinal plant demonstrates its potential to naturally provide anti-inflammatory and anti-oxidant with a special emphasis on anti-hypertensive and cardioprotective effects. The body of literature reports that the chemical composition of crude E. grandiflorus extracts are notably composed of diterpenoids and flavonoids metabolites. Pharmacological studies have shown that oral treatments using the hydroalcoholic extracts of leaves from this plant has a significant anti-inflammatory, anti-hypertensive, diuretic and cardioprotective effects in rats with no toxicity. The holistic activities of complex extracts are corroborated by the individuals mechanisms of action, as well as, synergistic benefits attributed to the isolated chemical major constituents in this species. In light of the serious health concerns ascribed, it is important to investigate medicinal plant species with histories of traditional use for circulatory problems to meet the growing demands by scientifically validating their use and safety.<br /> (Copyright © 2017 Elsevier Ltd. All rights reserved.)
- Subjects :
- Animals
Anti-Inflammatory Agents chemistry
Anti-Inflammatory Agents isolation & purification
Anti-Inflammatory Agents pharmacology
Antihypertensive Agents chemistry
Antihypertensive Agents isolation & purification
Antihypertensive Agents pharmacology
Brazil
Humans
Phytochemicals isolation & purification
Plant Extracts isolation & purification
Alismataceae chemistry
Phytochemicals chemistry
Phytochemicals pharmacology
Plant Extracts chemistry
Plant Extracts pharmacology
Plants, Medicinal chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1873-6351
- Volume :
- 109
- Issue :
- Pt 2
- Database :
- MEDLINE
- Journal :
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
- Publication Type :
- Academic Journal
- Accession number :
- 28322968
- Full Text :
- https://doi.org/10.1016/j.fct.2017.03.026