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[Analysis of short-term respiratory adverse events in 183 bronchial thermoplasty procedures].
- Source :
-
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases [Zhonghua Jie He He Hu Xi Za Zhi] 2017 Mar 12; Vol. 40 (3), pp. 176-181. - Publication Year :
- 2017
-
Abstract
- Objective: To analyze the short-term (3 weeks) adverse respiratory events after bronchial thermoplasty(BT) in patients with severe asthma. Methods: The China-Japan Friendship Hospital recruited 62 patients with severe asthma for BT treatment from March 2014 to July 2016, with a total of 183 BT procedures. The data of adverse respiratory events within 3 weeks after procedure were collected to analyze the factors that might potentially influence the occurrence of adverse events. Results: Forty-three patients (69.4%) experienced adverse respiratory events within 3 weeks after treatment. Totally 153 adverse respiratory events occurred after 87 procedures(47.5%). The main adverse events were cough (15 events, 8.20%), sputum production (37 events, 20.22%), temporary PEF reduction (37 events, 20.22%), chest distress (12 events, 6.56%), blood in sputum (11 events, 6.01%), asthma exacerbation (10 events, 5.46%), and pneumonia(6 events, 3.28%). Most events were relieved or resolved with standard therapy in 1 week. No severe adverse events including tracheal intubation, malignant arrhythmias or death occurred within 3 weeks after procedure. The baseline eosinophil percentage in induced sputum and blood, operation times, and preoperative FEV(1) (% predicted) might influence the occurrence of adverse events after treatment. Patients with preoperative FEV(1) (% predicted) ≥60% had lower risk of adverse events. Conclusion: BT showed a good security profile in treating patients with severe asthma within 3 weeks after procedure.
- Subjects :
- Adult
Bronchi pathology
China
Electric Stimulation Therapy adverse effects
Female
Forced Expiratory Volume
Humans
Hyperthermia, Induced
Leukocyte Count
Male
Respiratory Function Tests
Sputum
Treatment Outcome
Asthma surgery
Bronchi surgery
Cough complications
Electric Stimulation Therapy methods
Muscle, Smooth surgery
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1001-0939
- Volume :
- 40
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
- Publication Type :
- Academic Journal
- Accession number :
- 28297811
- Full Text :
- https://doi.org/10.3760/cma.j.issn.1001-0939.2017.03.007