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[Synchronous bilateral breast cancer: experiences in the Mohammed VI Cancer Treatment Center, CHU Ibn Rochd, Casablanca].
- Source :
-
The Pan African medical journal [Pan Afr Med J] 2016 Oct 27; Vol. 25, pp. 121. Date of Electronic Publication: 2016 Oct 27 (Print Publication: 2016). - Publication Year :
- 2016
-
Abstract
- Synchronous bilateral breast cancers (SBBC) are characterized by extensive clinical and morphological heterogeneity, with an frequency between 1.5 and 3.2%. Women treated for unilateral breast cancer are at higher risk of developing contralateral breast cancer. Screening and advances in breast imaging have improved detection rates of SBBC. Our study aims to analyze the epidemiological, clinical, histological and therapeutic features of bilateral breast cancer. We conducted a cross-sectional study of patients with breast cancer treated at the Mohammed VI Center over a two year period. Statistical analysis of the results was performed using R. software. 31 patients had SBBC, representing 2.4% of breast cancer cases in our Center. The average age was 47.8 ± 8.4 years, 22.6% of patients used oral contraceptives. A family history of breast cancer was observed in 22.6% of cases. The most common histological type was invasive ductal carcinoma (58.1%), SBR grade II and III were common (38.7%). Hormone receptors were positive for progesterone (38.7%) and for estrogen (41.9%). HER2 was overexpressed in 20.0% of cases. 29.0% of patients received hormonal therapy and 3.2% targeted therapies. Our study showed that bilateral breast cancer represents a small percentage of all breast cancers but have specific clinical features that help to differentiate it from unilateral breast cancer.<br />Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêt.
- Subjects :
- Adult
Aged
Breast Neoplasms therapy
Carcinoma, Ductal, Breast epidemiology
Carcinoma, Ductal, Breast therapy
Contraceptives, Oral administration & dosage
Cross-Sectional Studies
Female
Humans
Middle Aged
Morocco
Neoplasms, Multiple Primary therapy
Receptors, Estrogen metabolism
Receptors, Progesterone metabolism
Retrospective Studies
Breast Neoplasms pathology
Carcinoma, Ductal, Breast pathology
Neoplasms, Multiple Primary pathology
Subjects
Details
- Language :
- French
- ISSN :
- 1937-8688
- Volume :
- 25
- Database :
- MEDLINE
- Journal :
- The Pan African medical journal
- Publication Type :
- Academic Journal
- Accession number :
- 28292084
- Full Text :
- https://doi.org/10.11604/pamj.2016.25.121.9967