Back to Search Start Over

Twist of fate for skeletal muscle mesenchymal cells.

Authors :
Goloviznina NA
Kyba M
Source :
Nature cell biology [Nat Cell Biol] 2017 Mar 01; Vol. 19 (3), pp. 153-154.
Publication Year :
2017

Abstract

Skeletal muscles are composed of different types of fibres. Can these be thought of as distinct lineages with specific lineage-restricted progenitors? A provocative study now proposes that mesenchymal cells expressing the transcription factor Twist2 act as myogenic progenitors with selective type IIb fibre-differentiation potential.

Subjects

Subjects :
Animals
Humans
Muscle Fibers, Fast-Twitch cytology
Muscle, Skeletal metabolism
Satellite Cells, Skeletal Muscle cytology
Satellite Cells, Skeletal Muscle metabolism
Mesenchymal Stem Cells cytology
Muscle, Skeletal cytology
Transcription Factors metabolism

Details

Language :
English
ISSN :
1476-4679
Volume :
19
Issue :
3
Database :
MEDLINE
Journal :
Nature cell biology
Publication Type :
Academic Journal
Accession number :
28248307
Full Text :
https://doi.org/10.1038/ncb3482
Full Text Access
View/download PDF

Tools

Authors Abstract Subjects Details